Paracetamol( 4-Acetamidophenol) Paracetamol
CAS No.: 103-90-2
Molecular formula: C8H9NO2
Molecular weight: 151.16
EINECS number: 203-157-5
Melting point 168-172 °C (lit.)
Boiling point 273.17°C (rough estimate)
Storage conditions Store at RT
Uses Mainly used for fever caused by cold, headache and relieve mild to moderate pain, such as joint pain, muscle pain, neuralgia, migraine, dysmenorrhea, cancer pain and postoperative analgesia. It can also be used in patients who are allergic to aspirin, intolerant or unsuitable for aspirin: patients with chickenpox, hemophilia and other bleeding disorders (including those who have anticoagulant therapy), as well as patients with mild peptic ulcer and gastritis.
Description:
Paracetamol, also known as acetaminophen or APAP, is a medication used to treat pain and fever.It is typically used for mild to moderate pain relief.Evidence for its use to relieve fever in children is mixed.It is often sold in combination with other ingredients such as in many cold medications.In combination with opioid pain medication, paracetamol is also used for more severe pain such as cancer pain and pain after surgery. It is typically used either by mouth or rectally but is also available intravenously.Effects last between two and four hours.
Paracetamol is generally safe at recommended doses.Serious skin rashes may rarely occur, and too high a dose can result in liver failure.It appears to be safe during pregnancy and when breastfeeding.In those with liver disease, it may still be used, but in lower doses.Paracetamol is classified as a mild analgesic.It does not have significant anti-inflammatory activity and how it works is not entirely clear.
Paracetamol was discovered in 1877.It is the most commonly used medication for pain and fever in both the United States and Europe.It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system.Paracetamol is available as a generic medication with trade names including Tylenol and Panadol among others.The wholesale price in the developing world is less than 0.01 USD per dose.In the United States it costs about 0.04 USD per dose.
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